A fan recently quizzed Platinum Studios on whether they or Capcom would consider creating an Okami 2 sequel for Nintendo Wii U.
The original Ōkami was created by the now defunct Clover Studio, many of whom went on to work at Platinum Games, so a potential sequel is something the studio could develop given the go ahead from rights holder and publisher Capcom.
More recently an HD version of the PlayStation 2 edition was released at retail in Japan and is available as a downloadable title in Europe/North America on PlayStation 3.
Director Hideki Kamiya responded to requests for a Wii U version with simply "Ask Capcom".
If Capcom agree to a sequel, regardless of who develops it, would you be interested in Okami 2?